Alphagan® P 0.1% : About Glaucoma

Glaucoma risk factors

In the early stages of open-angle glaucoma, there are usually no symptoms. Most people are not aware that they have glaucoma until it is diagnosed by an eye doctor. That’s why it is so important that you keep your annual eye appointment. Although glaucoma can affect anyone, you may be at greater risk if one or more of the following describes you:

Risk Checklist

The best way to find out if you have glaucoma is to schedule an appointment with your eye doctor.

Indication: ALPHAGAN^® P 0.1% ophthalmic solution is approved for the lowering of intraocular pressure (IOP) in patients with open-angle glaucoma or ocular hypertension.

Important Safety Information
Contraindication: ALPHAGAN^® P 0.1% is contraindicated in patients receiving monoamine oxidase (MAO) inhibitor therapy.
Precautions: Although ALPHAGAN^® P 0.1% ophthalmic solution had minimal effect on the blood pressure of patients in clinical studies, caution should be exercised in treating patients with severe cardiovascular disease. ALPHAGAN^® P 0.1% should be used with caution in patients with depression, cerebral or coronary insufficiency, Raynaud's phenomenon, orthostatic hypotension, or thromboangiitis obliterans.
Adverse reactions: Adverse events occurring in approximately 10% to 20% of the subjects included: allergic conjunctivitis, conjunctival hyperemia, and eye pruritus. Adverse events occurring in approximately 5% to 9% included: burning sensation, conjunctival folliculosis, hypertension, ocular allergic reaction, oral dryness, and visual disturbance.

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1. National Eye Institute. Facts about glaucoma. National Eye Institute Web site. http://www.nei.nih.gov/health/glaucoma/glaucoma_facts.asp. Accessed August 16, 2009.
2. Mayo Clinic. Risk factors. Mayo Clinic Web site. http://www.mayoclinic.com/health/glaucoma/DS00283/DSECTION=risk-factors. Accessed July 2, 2009.