Efficacy equivalent to original ALPHAGAN®, with the lowest dose of active ingredient1 Gentle-to-the-eyes PURITE® preservative1 Low rate of allergy in pivotal trials (n = 215)2 Low rate of systemic adverse events in pivotal trials (n = 215)2 No substitutions at the pharmacy level Efficacy Coexisting Conditions Safety and Tolerability Dosage and Administration Patient Resources

Indication: ALPHAGAN® P 0.1% ophthalmic solution is indicated for the lowering of intraocular pressure (IOP) in patients with open-angle glaucoma or ocular hypertension. Important Safety Information Contraindication: ALPHAGAN® P 0.1% is contraindicated in patients receiving monoamine oxidase (MAO) inhibitor therapy. Precautions: Although ALPHAGAN® P 0.1% ophthalmic solution had minimal effect on the blood pressure of patients in clinical studies, caution should be exercised in treating patients with severe cardiovascular disease. ALPHAGAN® P 0.1% should be used with caution in patients with depression, cerebral or coronary insufficiency, Raynaud's phenomenon, orthostatic hypotension, or thromboangiitis obliterans. Adverse reactions: Adverse events occurring in approximately 10% to 20% of the subjects included: allergic conjunctivitis, conjunctival hyperemia, and eye pruritus. Please click here for full prescribing information. 1. ALPHAGAN® P Prescribing Information. 2. Data on file, Allergan, Inc.